YI Award Recipients 2013

Lu Yang, MD:

West China Hospital, Sichuan University

Mentors:

Qiang Wei, MD and Tianyong Fan, MD

Proposal Title:

Treating inflammation to prevent prostate cancer initiation and progression.

Shalini S. Yadav, PhD:

Mount Sinai School of Medicine

Mentors:

Ashutosh Tewari, MD

Project Title:

Intratumor Heterogeneity (ITH) in Prostate Cancer

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Daniel Thorek, PhD:

Johns Hopkins University

Mentors:

David Scheinberg, MD, PhD and Steve Larson, MD

Project Title:

Alpha-particle therapy by 225Actinium-labeled prostate kallikrein-specific antibody to eradicate advanced disease

Nicole Simone, MD:

Thomas Jefferson University

Mentors:

Adam Dicker, MD, PhD, Karen Knudsen, PhD and Peter Carroll, MD

Project Title:

Metabolic approaches for targeting multiple components of the IGF-1R pathway in prostate cancer

Matthew Schiewer, PhD:

Thomas Jefferson University

Mentor:

Karen Knudsen, PhD

Project Title:

Determining the translation capacity of the PARP-1/AR axis in prostate cancer

Jennifer Rider, ScD:

Harvard School of Public Health

Mentors:

Lorelei Mucci, ScD and Myles Brown, MD

Project Title:

The immunomodulatory and androgen-associated actions of vitamin D in prostate cancer

Colin Pritchard, MD, PhD:

University of Washington

Mentors:

Peter Nelson, MD

Project Title:

Targeting the ‘Hypermutated Subtype’ of Prostate Cancer: From Mechanism to Implementation of Genomic Testing for Precision Therapy”

Niv Papo, PhD:

Ben-Gurion University of the Negev (Israel)

Mentor:

Eyal Mishani, PhD

Project Title:

Developing novel dual-specific proteins that target multiple receptors for applications in prostate cancer imaging and therapy

Antonina Mitrofanova, PhD:

Rutgers, The State University of New Jersey

Mentor:

Michael Shen, PhD

Project Title:

A systems biology approach to identify and evaluate novel drug targets for aggressive prostate cancer

Rohit Mehra, MD:

University of Michigan School of Medicine

Mentor:

Arul Chinnaiyan, MD, PhD

Project Title:

Clinicopathological characterization of novel lncRNAs in prostate cancer risk stratification

PCF Awards:

2013 PCF Young Investigator Award

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Theodoros Karantanos, MD:

MD Anderson Cancer Center

Mentors:

Timothy Thompson, PhD and Christopher Logothetis, MD

Project Title:

The role of aerobic glycolysis in the development of castrate resistant prostate cancer

Hao Hu, MD, MBBS:

People’s Hospital, Peking University

Mentors:

Kexin Xu, MD, MBBS and Xiaofeng Wang, MBBS

Project Title:

EMI1 and its role in prostate cancer initiation and progression.

Vivek Arora, MD, PhD:

Washington University

Mentor:

Charles Sawyers, MD

Project Title:

Defining strategies to overcome enzalutamide (Xtandi) resistance

Jennifer Bishop, PhD:

University of British Columbia

Mentors:

Martin Gleave, MD and Amina Zoubeidi, PhD

Project Title:

Regulation of cell plasticity by the androgen receptor: A novel mechanism of enzalutamide (Xtandi) resistance

Irfan Asangani, PhD:

University of Michigan

Mentor:

Arul Chinnaiyan, MD, PhD

Project Title:

Characterization and therapeutic targeting of MMSET in prostate cancer

Qi Cao, PhD:

Houston Methodist Research Institute

Mentor:

Arul Chinnaiyan, MD, PhD

Project Title:

A novel role for Polycomb Group proteins in androgen signaling and prostate cancer

Charles Chan, PhD:

Stanford University School of Medicine

Mentors:

Irving Weissman, MD and Michael Longaker, MD

Project Title:

Identification and therapeutic targeting of cancer stem cell niche interactions in metastatic prostate bone marrow disease

Chia-Yi Chu, PhD:

Cedars-Sinai Medical Center

Mentor:

Leland Chung, PhD

Project Title:

Metastasis-initiating cells (MICs) as predictors of lethal progression of human prostate cancer

Michael Evans, PhD:

University of California, San Francisco

Mentors:

Charles Sawyers, MD and Jason Lewis, PhD

Project Title:

Exploiting the genetics of advanced prostate cancer for tumor detection and therapy with transferrin-based radionuclides

Jason A. Efstathiou, MD, DPhil:

Massachusetts General Hospital

Mentor:

Matthew R. Smith, MD, PhD

Project Title:

Predictors of Response and Failure to Radiotherapy for Prostate Cancer in a Randomized Trial

Geraldine Gueron, PhD:

Iquibicen-Conicet (Argentina)

Mentor:

Elba Vazquez, PhD

Project Title:

Proteome-base biomarkers in prostate cancer: protein profiling using mass spectrometry, bioinformatics based approach and tissue microarray technology

Mentors:

Philip Kantoff, MD and Christopher Sweeney, MBBS

Project Title:

Clinical exploration of innovative targeted and immune modulating therapies in prostate cancer

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Emmanuel Antonarakis, MD:

Johns Hopkins University School of Medicine

Mentors:

Michael Carducci, MD and Jun Luo, PhD

Project Title:

Understanding mechanisms of response and resistance to abiraterone (Zytiga) and enzalutamide (Xtandi) in men with metastatic castration-resistant prostate cancer, by interrogation of tumor biopsies for androgen receptor splice variants.

Syed Adnan Ali, MD:

Mount Sinai School of Medicine

Mentor:

Ashutosh Tewari, MD

Project Title:

Intratumor Heterogeneity (ITH) in Prostate Cancer