In memory of Lyle Pauley

Thank you for considering a donation to the Prostate Cancer Foundation in honor of Lyle Pauley. His 12-year fight against prostate cancer concluded on October 19, 2012, at the age of 71.

Lyle’s original 2000 diagnosis came with a Gleason score of 9. Following a prostatectomy in 2001, Lyle began researching his disease in earnest. When his PSA jumped in 2004 his urologist predicted a life expectancy of 18 months. Later an oncologist started Lyle on intermittent hormone therapy. On his own, Lyle pursued a two-pronged approach of traditional medical treatment combined with more holisitic treatment addressing the physical and nutritional aspects of healing and recovery. He was particularly disciplined in following strict nutritional guidelines and routine vigorous exercise.

As his cancer became hormone resistant, Lyle pursued chemotherapy followed by cellular immunotherapy (Provenge). Lyle’s cancer more recently responded positively to androgen blocking medication (Zytiga). Throughout his battle, Lyle kept up-to-date on the most promising therapies in prostate cancer research and refused to accept there were no more alternatives. Something new in prostate cancer research was always coming and he was excited to see several promising therapies get fast-tracked for FDA approval.

It is with this hope that we encourage you to support the Prostate Cancer Foundation, the world’s largest philanthropic source of support for prostate cancer research.

Terms to know from this article:


Gleason Score (GS) - Gleason Grade: A system of grading prostate cancer cells based on how they look under a microscope. Gleason scores range from 2 to 10 and indicate how likely it is that a tumor will spread. A low Gleason score means the cancer cells are similar to normal prostate cells and are less likely to spread; a high Gleason score means the cancer cells are very different from normal and are more likely to spread.


An operation to remove part or all of the prostate. Radical (or total) prostatectomy is the removal of the entire prostate and some of the tissue around it.


A doctor who has special training in diagnosing and treating diseases of the urinary organs in females and the urinary and reproductive organs in males.


A doctor who specializes in treating cancer. Some oncologists specialize in a particular type of cancer treatment. For example, a radiation oncologist specializes in treating cancer with radiation.


A chemical made by glands in the body. Hormones circulate in the bloodstream and control the actions of certain cells or organs. Some hormones can also be made in a laboratory.


Immunotherapy is a type of treatment that boosts or restores the immune system to fight cancer, infections and other diseases. There a several different agents used for immunotherapy; Provenge is one example.


A type of hormone that promotes the development and maintenance of male sex characteristics.


prostate-specific antigen (PSA): A substance produced by the prostate that may be found in an increased amount in the blood of men who have prostate cancer, benign prostatic hyperplasia, or infection or inflammation of the prostate.