05/22/2017

Prostate cancer cells that commit identify fraud

A new study reported at the 2017 American Association for Cancer Research (AACR) Annual Meeting identified new mechanisms and treatment approach for an aggressive subtype of AR-therapy resistant prostate cancer. Prostate cancers are fueled by male hormones called androgens.  These growth signals are transmitted to cancer cells through the androgen... Read More

05/02/2017

Why has checkpoint immunotherapy been ineffective in treating prostate cancer?

Checkpoint immunotherapy, the relatively new type of cancer treatment making headlines for being able to seemingly cure some patients with melanoma and other cancers, has been notoriously ineffective in prostate cancer.  At the 2017 American Association for Cancer Research (AACR) Annual Meeting, Dr. Padmanee Sharma presented the discovery of at... Read More

04/20/2017

Tumor-targeting CAR T cell immunotherapy finally works in solid tumors; soon to be in trials for prostate cancer

Immune cells that are genetically engineered with designer molecules to recognize and kill cancer cells may sound like an episode of science fiction, and for solid tumors, they used to be – until now.  At the 2017 American Association for Cancer Research (AACR) Annual Meeting, City of Hope National Cancer... Read More

02/14/2017

Prostate Cancer Foundation Announces New Recipients of 2016 PCF Challenge Awards to Promote Research in Deadly Prostate Cancer

SANTA MONICA, CA Feb. 14, 2017 – The Prostate Cancer Foundation (PCF) today announced that it has granted eight new 2016 PCF Challenge Awards to advance treatments and cures for metastatic or currently incurable prostate cancer.  PCF Challenge Awards are multi-year awards supporting cross-disciplinary teams of research scientists.  In 2016,... Read More

10/24/2016

Genetic Counseling Center Dedicated To Advanced Prostate Cancer Opens In Seattle

Prostate cancer is one of the most heritable forms of cancer. Hereditary mutations in “DNA repair” genes – BRCA1, BRCA2, and others – which are best known for their association with breast and ovarian cancer predisposition, are now known to be associated with advanced prostate cancer. In fact, ~12% of... Read More

08/30/2016

The Prostate Cancer Foundation’s 2016 Coffey-Holden Prostate Cancer Academy Meeting Accelerates Advances In The Understanding And Treatment Of Metastatic Prostate Cancer

The Prostate Cancer Foundation (PCF) has a legacy of not only funding the most impactful research in prostate cancer, but also creating new infrastructures, global knowledge networks, and research initiatives that support and accelerate prostate cancer research towards better treatment for advanced prostate cancer patients. For the past four years,... Read More

07/15/2016

New study finds one in nine men with metastatic prostate cancer carry inherited mutations in DNA repair genes with important implications for treatment and for cancer risk in family members

https://vimeo.com/739319237/15d67dee4f Cancer, the uncontrolled growth of cells, is caused by the acquisition of genetic mutations that allow cells to evade the normal biological laws governing when and where they can grow in the body. Mechanisms that maintain the accuracy of our genomes are critical for preventing cells from collecting mutations... Read More

06/07/2016

New Clinical Trial Endpoint May Speed The Development Of New Therapies For Patients With Localized Prostate Cancer

At the 2016 American Society of Clinical Oncology (ASCO) Annual Conference, Dr. Christopher Sweeney presented results from ICECaP (Intermediate Clinical Endpoints in Cancer of the Prostate), a Prostate Cancer Foundation (PCF)-supported initiative, that will halve the time required to assess new therapies for aggressive prostate cancer. "We need to move... Read More

05/13/2016

Obesity And A High-fat Diet Promote Prostate Cancer Progression By Amplifying The Activity Of Cancer Genes

At the 2016 Annual American Association for Cancer Research (AACR) Conference, Giorgia Zadra, PhD, of the Harvard: Dana-Farber Cancer Institute and Brigham and Women's Hospital, presented results from a study that helped to clarify the relationship between obesity and prostate cancer. The skinny? Fat increases the activity of a critical... Read More

05/02/2016

Inherited Defects In Breast And Ovarian Cancer Genes Predispose To Prostate Cancer With Worse Outcomes

At the 2016 American Association for Cancer Research (AACR) Annual Meeting, Dr. Joaquin Mateo, a medical oncologist at the Institute for Cancer Research, UK, presented results from a new study which assessed hormone therapy-resistant prostate cancer patients for the prevalence of hereditary alterations in DNA repair genes. An estimated 50-60%... Read More