Defining Targets and Biomarkers in Prostate Cancer Stem Cells: New Therapeutic Opportunities
About Defining Targets and Biomarkers in Prostate Cancer Stem Cells: New Therapeutic Opportunities
Cancer stem cells are an elusive, small subpopulation of tumor cells that are not only resistant to therapy but also repopulate a solid tumor after most tumor cells are killed by a therapy. Understanding the biology of cancer stem cells and targeting their elimination is a priority in cancer research. Dr. Witte and his team at UCLA and the Salk Institute of Biological Studies are world leading experts in cancer stem cell biology. This team will now direct their expertise toward studies of prostate cancer stem cells. Application of new genetic biotechnologies will better define this critical tumor cell population and will reveal therapeutic targets.
Research team members: Dr. Pei-Yu E. Chiou, UCLA; Dr. Isla P. Garraway, UCLA; Dr. Michael A. Teitell, UCLA; Dr. Hong Wu, UCLA; Dr. Inder M. Verma, The Salk Institute.
Dr. Owen N. Witte, UCLA