Epigenetic Strategies in Androgen Receptor-Dependent Interchromosomal Networking and Translocation

About Epigenetic Strategies in Androgen Receptor-Dependent Interchromosomal Networking and Translocation

Epigenetics is a relatively new area of cancer biology that describes genetic regulation which is independent from DNA sequence. Cancer occurs due to both mutation and epigenetic alterations resulting in dysregulation of growth control. Only recently have scientists discovered epigenetic changes in tumor cells that can be controlled with new medicines. Dr. Rosenfeld and his expert team propose the application of a new genetic biotechnology to discover genetic and epigenetic changes resulting in prostate cancer. The overall goal of this work is the discovery of new medications that control prostate cancer when all existing treatments have failed.
Research team members: Dr. Xiang-Dong Fu, University of California, San Diego; Dr. Sheng S. Ding, The Scripps Research Institute.

Lead Investigator:

Dr. Michael G. Rosenfeld, University of California, San Diego