Ram S. Mani

About Ram S. Mani

Gene fusions in prostate cancer are early genetic alterations thought to initiate the process of cancer growth. These fusions are defined by the joining of two genes normally found in distinct regions of the genome. Dr. Mani proposes to exploit this finding by identifying molecules that block the cellular machinery responsible for generating gene fusions, thereby preventing prostate cancer initiation or progression. The identification of such molecules would define a new class of anti-cancer medicines that could slow cancer progression and may enhance the efficacy of existing treatments.

Award

The 2010 Stewart Rahr – PCF Young Investigator Award

Ram S. Mani, PhD

University of Michigan – Ann Arbor, MI

Mentor:

Arul Chinnaiyan, MD, PhD, Howard Hughes Medical Institute Investigator, Director of Pathology Research Informatics, Director of Cancer Bioinformatics, S.P. Hicks Endowed Professor of Pathology, American Cancer Society Research Professor, Professor of Urology, at the University of Michigan.