2019 Igor Tulchinsky – PCF VAlor Young Investigator Award

Developing a prostate cancer data repository to support implementation of precision oncology care and research in VA

Jeremy Shelton, MD
University of California, Los Angeles (UCLA)

Mentors: Matthew Rettig

Description:

  • Prostate cancer is the most common solid tumor diagnosis among U.S. veterans, accounting for 31.8% of all cancer diagnoses at the VA in 2012. 8% of men with new prostate cancer diagnoses in the VA have advanced disease.
  • The PCF and the VA have developed a novel partnership to drive rapid implementation of precision medicine for veterans with prostate cancer.
  • Jeremy Shelton will create a prostate cancer data core to serve the operational and research objectives of the VA/PCF partnership. This data core will contain clinical, genomic, and research data for prostate cancer patients seen in the VA.
  • Clinical infrastructures will be developed to streamline delivery of optimal individualized care to VA patients and match patients with precision medicine clinical trials. These infrastructures will include operational structures, advisory committees, decision support tools, and pathways to integrate with non-VA institutions.
  • If successful, this project will result in the establishment of a rich data core and precision medicine delivery system that will significantly improve outcomes for veterans with prostate cancer and will drive new research into prostate cancer biology and treatment.

What this means to patients:  Dr. Shelton will establish a data core and clinical infrastructure at the VA to accelerate widespread adoption of precision oncology for veterans with prostate cancer, and create a roadmap for improving care for the treatment of many other diseases at the VA.on.