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Which Procedure is Better – Robotic or Open Prostatectomy?

“Robot vs. Human Prostatectomy: It’s a Tie, At Least So Far.” “Robots as Good as Human Surgeons, Study Finds.” Headlines can be deceptive and not very helpful if you’re trying to choose the right treatment for prostate cancer. From these headlines, it almost sounds like an event took place –. Read More


Progress Report: Andrea Harzstark, MD

Investigator: Andrea Harzstark, MD – Assistant Professor, University of California, San Francisco Tobacco and Prostate Cancer Therapy: The Missing Link? Prostate cancer affects one in every six American men; ~25% of those men are smokers. Smoking causes many health risks, including a higher risk for lung cancer. Many of the. Read More


Progress Report: Steven Frank, MD

Investigator: Steven Frank, MD– Assistant Professor, University of Texas, M.D. Anderson Cancer Center C4 and MRI-based Prostate Brachytherapy Brachytherapy is a form of radiotherapy where a radiation source, called “seeds”, is precisely implanted into the prostate such that emitted radiation will abolish the tumor. Recent technological advances have increased the. Read More


Progress Report: Adam S. Feldman, MD, MPH

Investigator: Adam S. Feldman, MD, MPH–Assistant Professor of Surgery, Massachusetts General Hospital, Harvard School of Medicine Active Surveillance: Identifying When to Treat and When Not to Treat In 2010 nearly 218,000 men will be diagnosed with prostate cancer in the United States. However, ~50% of those men will have low. Read More


Progress Report: Eleni Efstathiou, MD, Ph.D

Investigator: Eleni Efstathiou, MD, PhD – Assistant Professor, University of Texas, M.D. Anderson Cancer Center Biomarker Driven Application of Therapy Androgens (male hormones such as testosterone) fuel prostate cancer growth and survival. Androgens are synthesized in the testis and adrenal glands. Therapeutic agents that block the production of androgens (androgen. Read More


Progress Report: Scott Dehm, Ph.D

Investigator: Scott Dehm, PhD – Assistant Professor, University of Minnesota Mechanisms of Androgen Receptor (AR) Activation in Prostate Cancer The standard first line treatment strategy for metastatic prostate cancer is androgen (male hormones) deprivation therapy, such as Lupron, which reduces the level of circulating testosterone (type of androgen), or such. Read More


Progress Report: Atish Choudhury, MD, Ph.D

Investigator: Atish Choudhury, MD, PhD – Instructor in Medicine, Dana-Farber Cancer Institute Molecular Determinants of Hormone Refractory Prostate Cancer Metastatic prostate cancer initially responds to androgen deprivation therapy (ADT; blockade of male hormones such as testosterone) resulting in tumor regression and improved clinical performance. This is because prostate cancer cell. Read More


Progress Report: Gerhardt Attard, MD, Ph.D

Investigator: Gerhardt Attard, MD, PhD – Assistant Professor, Institute for Cancer Research, Royal Marsden Hospital, London Predicting Resistance to Abiraterone: Molecular Analysis of CTCs First-line treatment for recurrent prostate cancer involves blockade of male hormone (testosterone; androgen) production in a process known as androgen deprivation therapy (ADT). Androgens are synthesized. Read More


Progress Report: Mohamed Simon Arredouani, Ph.D

Investigator: Mohamed Simon Arredouani, PhD – Assistant Professor, Beth Israel Deaconess Medical Center Advances in Prostate Cancer Immunotherapy The immune system protects humans and other mammals from disease by recognizing foreign invaders such as bacteria and viruses. It is also thought that tumor cells express molecules foreign to the patient. Read More


Progress Report: John Ward, MD

Investigator: John Ward, MD– Assistant Professor, M.D. Anderson Cancer Center, University of Texas Noninvasive Radiofrequency Field for the Targeted Destruction of Prostate Cancer Using Directed Gold Nanoparticles—Activated Gold Particles Could Provide Novel Means of Destroying Tumors Dr. Ward is investigating a new way to kill prostate cancer cells by targeting. Read More