YI Award Recipients 2015

Institution:

University of Michigan

Mentors:

Arul Chinnaiyan, MD, PhD; Felix Feng, MD

Proposal Title:

Investigating Long Noncoding RNAs in Aggressive Prostate Cancer

Rendong Yang, PhD:

University of Minnesota

Mentor:

Scott Dehm, PhD

Proposal Title:

Delineating Coding and Regulatory Indels in Prostate Cancer

Adam Sowalsky, PhD:

National Cancer Institute

Mentors:

Kathleen Kelly, PhD; William Dahut, MD

Proposal Title:

Investigations into the Mechanisms of Resistance to Enzalutamide in CRPC

Prasanna Sooriakumaran, MBBS, PhD:

University of Oxford

Mentor:

Freddie C. Hamdy, MD

Proposal Title:

Improving Quality of Care for Men with Skeletal Metastases from Prostate Cancer: Defining the Burden-of-Treatment and its Management, and Developing Models to Predict Quality-of-Life

Shabnam Shalapour, PhD:

University of California, San Diego

Mentor:

Michael Karin, PhD

Proposal Title:

Development of Immunosuppressive Plasmocytes that Interfere with T-Cell-Dependent Immunogenic Chemotherapy in Prostate Cancer

Saul Priceman, PhD:

City of Hope National Medical Center

Mentor:

Stephen Forman, MD

Proposal Title:

Targeting Metastatic Prostate Cancer with PSA-Specific Chimeric Antigen Receptor-Engineered T-Cells

Sean McGuire, MD, PhD:

Baylor College of Medicine

Mentor:

Bert O’Malley, MD

Proposal Title:

Targeting the Mitochondrial Pyruvate Carrier in Castration- Resistant Prostate Cancer

Ravi Madan, MD:

National Cancer Institute

Mentor:

James Gulley, MD, PhD

Proposal Title:

Using A Therapeutic Cancer Vaccine to Enhance Anti-PD-1 Therapy Prior to Prostatectomy

Zhenfei Li, PhD:

Cleveland Clinic Foundation

Mentors:

Nima Sharifi, MD; Eric Klein, MD

Proposal Title:

A Novel Abiraterone Metabolite as a Predictive Biomarker for Clinical Response to Abiraterone

John Kyung Lee, MD:

University of Washington

Mentor:

Owen Witte, MD

Proposal Title:

Therapeutic Targeting of N-Myc-Driven Human Small Cell Neuroendocrine Prostate Cancer

Vishal Kothari, PhD:

University of Michigan

Mentors:

Arul Chinnaiyan, MD, PhD; Felix Feng, MD

Proposal Title:

Investigating DNAPK as a Therapeutic Target and a Prognostic Biomarker in Castration-Resistant Prostate Cancer

Won Kim, MD:

University of California, San Francisco

Mentors:

Charles Ryan, MD; Eric Small, MD

Proposal Title:

Dissecting Variant Androgen Signaling Phenotypes to Guide Treatment Selection in Abiraterone Acetate and Enzalutamide-Resistant Prostate Cancer

Joseph Ippolito, MD, PhD:

Washington University School of Medicine in St. Louis

Mentors:

Jeffrey Arbeit, MD; Farrokh Dehdashti, MD

Proposal Title:

Characterizing and Imaging Metabolic Symbiosis in Castrate- Resistant Prostate Cancer

Amanda Hargrove, PhD:

Duke University

Mentors:

Hashim Al-Hashimi, PhD; Peter Dervan, PhD

Proposal Title:

Targeting the lncRNA SChLAP1 in Aggressive Prostate Cancer by the Assembly of Multivalent Small Molecule Inhibitor

Justin Drake, PhD:

Rutgers University Cancer Institute of New Jersey

Mentor:

Robert DiPaola, MD

Proposal Title:

Elucidating Kinase Activation Pathways in Advanced Prostate Cancer

Heather Cheng, MD, PhD:

University of Washington

Mentor:

Peter Nelson, MD

Proposal Title:

Identifying High-Penetrance Prostate Cancer Risk Genes: Leveraging Families for Next Generation Discovery and Prevention

Institution:

Memorial Sloan Kettering Cancer Center