If you or someone you care about has been newly diagnosed with prostate cancer, this section will help guide you through the complexities of this diagnosis and other issues to consider.
The 2018 Patient Guide is here
Enter your email address to get the free pdf
Understanding Your Diagnosis
A doctor typically diagnoses prostate cancer after closely examining biopsy cells through a microscope. There are several types of cells in the prostate, and each contributes in its own way to the prostate’s development, architecture, and function.
But cancer cells grow in an uncontrolled way and look different than normal prostate cells. Pathologists look for these abnormal differences first to detect the presence of cancer and then to determine the cancer grade.
The Gleason grading system accounts for the five distinct patterns that prostate tumor cells tend to go through as they change from normal cells to tumor cells. The higher the score, the more aggressive the tumor.
The cells are scored on a scale from 1 to 5:
- “Low-grade” tumor cells (those closest to 1) tend to look very similar to normal cells.
- “High-grade” tumor cells (closest to 5) have mutated so much that they often barely resemble the normal cells.
The Gleason Score
The pathologist looking at the biopsy sample assigns one Gleason grade to the most predominant pattern in your biopsy and a second Gleason grade to the second most predominant pattern. The two grades added together determine your Gleason score (between 2 and 10).
Generally speaking, cancers with lower Gleason scores (2 – 4) tend to be less aggressive, while cancers with higher Gleason scores (7 – 10) tend to be more aggressive.
It’s also important to know whether any Gleason 5 is present, even in just a small amount, and most pathologists will report this. Having any Gleason 5 in your biopsy or prostate puts you at a higher risk of recurrence.
Guys: Don't Put it Off...
While each patient’s battle with prostate cancer is an individual one, my experience is hardly unique. My story began 4 years ago, back in 2011, when my wife...
Not Your Father's Prostate Cancer
Over the last two decades, the death rate from prostate cancer has declined more than 50%. In itself, this is a monumental accomplishment that can...
About the Prostate Cancer Foundation
The Prostate Cancer Foundation (PCF) is the world’s leading philanthropic organization funding and accelerating prostate cancer research. Every [shortcode id="17212"] minutes a man is diagnosed with...
The Gleason Score
What is a Gleason Score? After the biopsy of your prostate cancer, your doctor will explain the results to you using something called a Gleason...