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Genomic Landscape of Metastatic Prostate Cancer Unveiled in New Study

A comprehensive genetic analysis of metastatic prostate cancer has, for the first time, revealed a number of major ways in which abnormal alterations of the genome propel this aggressive form of the disease. As reported in the July 19, 2018 issue of Cell, a team led by investigators at UC... Read More


NIH and Prostate Cancer Foundation launch large study on aggressive prostate cancer in African-American men

The largest coordinated research effort to study biological and non-biological factors associated with aggressive prostate cancer in African-American men has begun. The $26.5 million study is called RESPOND, or Research on Prostate Cancer in Men of African Ancestry: Defining the Roles of Genetics, Tumor Markers, and Social Stress. It will... Read More


Deadly Form of Advanced Prostate Cancer is Common, Calls for Distinct Treatment

Original article issued by UCSF News. A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer. Previously, it... Read More


Tumors Grown in the Lab Provide Insights on Rare Prostate Cancer

Original article issued by Weill Cornell Medicine. Growing miniature tumors from patient’s cells in the laboratory may help scientists personalize treatments for those with a rare form of prostate cancer, according a study by Weill Cornell Medicine and NewYork-Presbyterian scientists. Patients with prostate cancer often receive therapies that reduce levels... Read More


How Your Spit May Help Doctors Diagnose Prostate Cancer

Original article issued by Healthline. It might seem inconceivable that a simple saliva test can tell you your chances of developing cancer. But evidently it can. And the reason is crude but simple: Your genetic makeup can be found in your spit. Scientists are now able to extract DNA from cells... Read More


Researchers find prostate cancer drug byproduct can fuel cancer cells

Original press release issued by: Cleveland Clinic. A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with... Read More


Non-coding DNA reveals a route by which advanced prostate cancer resists treatment

More than three quarters of metastatic prostate cancers that resist hormone-blocking therapies may harbor several duplicates of both the gene for a treatment resistance factor called the androgen receptor (AR) and of a never-before-seen genetic switch, or enhancer, that boosts the gene's expression. The duplications, as well as epigenetic signs... Read More


Why More Men Are Delaying Treatment for Prostate Cancer

Original article issued by Healthline. When Ben Pfeiffer was diagnosed with prostate cancer in April, his urologist noted in the biopsy report that he was leaning toward recommending that Pfeiffer have his prostate surgically removed. But Pfeiffer, 58, a married construction supervisor from Las Vegas with two grown daughters, said... Read More


VA Healthcare System Successfully Reduces ‘Rush to Treatment’ Rates for Low-Risk Prostate Cancer, Study Shows

May 15, 2018 - Record numbers of American veterans diagnosed with nonaggressive prostate cancer are heeding the advice of international medical experts and opting out of immediate surgery or radiation to treat their cancer. Instead, according to a study led by researchers at NYU School of Medicine, Perlmutter Cancer Center,... Read More


2018 AACR-Prostate Cancer Foundation Scholar-in-Training Award Recipients

Mark P. Labrecque, PhD University of Washington, Seattle, WA Abstract # 1092 Defining the molecular phenotypes of metastatic castration-resistant prostate cancer sensitive to FGF pathway inhibition M. P. Labrecque1, L. G. Brown1, I. M. Coleman2, L. D. True1, L. Kollath1, B. Lakely1, Y. C. Yang2, H. M. Nguyen1, E. Corey1,... Read More