2022 Igor Tulchinksy-Leerom Segal-PCF Challenge Award
Leveraging Poison Introns for Therapeutics and Diagnostics of Lethal Prostate Cancer
Principal Investigators: Mark Rubin, MD (University of Bern), Gunnar Rätsch, PhD (ETH Zurich), Rahul Kanadia, PhD (University of Connecticut)
Co-Investigators: Anke Augspach, PhD (University of Bern), Andre Kahles, PhD (ETH Zurich), Takemoto Kazumasa, PhD (University of Connecticut)
2022 PCF Challenge Award
Enhancing Antigen Presentation and Antitumor Immunity for Prostate Cancers Through an Intratumorally Delivered, Fc-Enhanced Anti-CD40 Antibody Therapy
Principal Investigators: Howard Scher, MD (Memorial Sloan Kettering Cancer Center), Behfar Ehdaie, MD, MPH (Memorial Sloan Kettering Cancer Center), David Knorr, MD, PhD (Memorial Sloan Kettering Cancer Center), Matthew Dallos, MD (Memorial Sloan Kettering Cancer Center)
Co-Investigators: Andrea Are, PhD (Memorial Sloan Kettering Cancer Center), Anuradha Gopalan, MD (Memorial Sloan Kettering Cancer Center), Christopher Gaffney, MD (Memorial Sloan Kettering Cancer Center)
2022 PCF Challenge Award
Targeting B7-H3 in Aggressive Variant Prostate Cancer
Principal Investigators: Di Zhao, PhD (The University of Texas MD Anderson Cancer Center), Ana Aparicio, MD (The University of Texas MD Anderson Cancer Center), Sangeeta Goswami, MD, PhD (The University of Texas MD Anderson Cancer Center)
Co-Investigator: Wenyi Wang, PhD (The University of Texas MD Anderson Cancer Center)
Young Investigator: Wei Shi, PhD (The University of Texas MD Anderson Cancer Center)
Collaborators: Nora Navone, MD, PhD (The University of Texas MD Anderson Cancer Center), James Allison, PhD (The University of Texas MD Anderson Cancer Center)
2022 PCF – Janssen Special Challenge Award
Advancing the Drug Development Process in Metastatic Prostate Cancer through Machine Learning
Principal Investigators: Eric Small, MD (University of California, San Francisco), Rahul Aggarwal, MD (University of California, San Francisco), Julian Hong, MD, MS (University of California, San Francisco), David Quigley, PhD (University of California, San Francisco)
Co-Investigators: Meera Chappidi, MD, MPH (University of California, San Francisco), Adam Foye, BS (University of California, San Francisco), Li Zhang, PhD (University of California, San Francisco)
2022 Count Me In-PCF Special Challenge Award for Metastatic Prostate Cancer
Metastatic Prostate Cancer (MPC) Project
Principal Investigators: Eliezer Van Allen, MD (Harvard: Broad Institute of MIT & Harvard)
Co-Investigators: Ben Zola, BS (Harvard: Broad Institute of MIT & Harvard), Parker Chastain, MPH (Harvard: Broad Institute of MIT & Harvard), Elana Anastasio, BA (Harvard: Broad Institute of MIT & Harvard), and Matias Vergara, MS (Harvard: Broad Institute of MIT & Harvard)