2024 Igor Tulchinsky – PCF VAlor Challenge Award
Germline Genomic and Clinical Predictors of Prostate Cancer Outcomes and Treatment Toxicity in the ProtecT Randomized Trial
Principal Investigators: Tyler Seibert, MD, PhD (University of California, San Diego), Freddie Hamdy, MD (University of Oxford, UK), Jenny Donovan, PhD (University of Bristol, UK), Richard Martin, PhD (University of Bristol, UK), Paul Boutros, PhD (University of California Los Angeles)
Co-Investigators: Emma Turner, PhD (University of Bristol, UK), Athene Lane, PhD (University of Bristol, UK), Rajeev Kumar, PhD (University of Oxford, UK), Sarah Kerns, PhD (Medical College of Wisconsin), Lee-Jen Wei, PhD (Harvard University; Harvard T.H. Chan School of Public Health)
Young Investigator: Roni Haas, PhD (University of California Los Angeles)
2024 The John Black Charitable Foundation – PCF Challenge Award
Developing Novel and Transformative Therapeutic Strategies Targeting mRNA translation for the Treatment of Molecularly Defined Prostate Cancer Subtypes
Principal Investigators: Adam Sharp, MD, PhD (The Institute of Cancer Research, London, UK), Johann de Bono, MD, PhD (The Institute of Cancer Research, London, UK), Andrew Hsieh, MD (Fred Hutchinson Cancer Center), Marco Bezzi, PhD (The Institute of Cancer Research, London, UK)
Young Investigators: Joe Taylor, PhD, (The Institute of Cancer Research, London, UK), Steven Blinka, MD, PhD (Fred Hutchinson Cancer Center)
2024 PCF Challenge Award (Anonymous)
Combination of POLQ inhibitor plus PARP inhibitor for HR-deficient and ATM-deficient Prostate Cancer
Principal Investigators: Alan D’Andrea, MD (Harvard: Dana-Farber Cancer Institute), Peter Nelson, MD (Fred Hutchinson Cancer Center)
Co-Investigators: Geoffrey Shapiro, MD, PhD (Dana-Farber Cancer Institute), Michael Haffner, MD, PhD (Fred Hutchinson Cancer Center)
Young Investigators: Jacob Berchuck, MD (Dana-Farber Cancer Institute), Stephanie Siegmund, MD (Brigham and Women’s Hospital), Galina Semenova, MD, PhD (Fred Hutchinson Cancer Center)
Collaborators: Bose Kochupurakkal, PhD (Dana-Farber Cancer Institute), Yuna Hirohashi, BS (Dana-Farber Cancer Institute), Roman Gulati, MSc (Fred Hutchinson Cancer Center), Ilsa Coleman (Fred Hutchinson Cancer Center)
2024 PCF VAlor Challenge Award
Donors: Anonymous, Patrice and Precious Motsepe (Motsepe Foundation), Stephen and Christine Schwarzman, Leerom and Karolina Segal, Cindy and Rob Citrone (Citrone 33), David and Kristin Steinberg
Plant Based Dietary Patterns and Advanced Prostate Cancer
Principal Investigators: Stacy Loeb, MD, MSc, PhD (Hon) (New York University Langone Health), Lorelei Mucci, ScD, MPH (Harvard T.H. Chan School of Public Health)
Co-Investigators: Edward Giovannucci, MD, ScD (Harvard T.H. Chan School of Public Health), Jaime Hart, ScD (Brigham and Women’s Hospital, Harvard Medical School), Konrad Stopsack, MD ( Harvard T.H. Chan School of Public Health), Martha Shrubsole, PhD (Vanderbilt University)
Young Investigator: Natasha Gupta, MD, MSc (Manhattan Veterans Affairs and New York University Langone Health)