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Poster Abstracts

The deadline for submitting abstracts for poster presentations at the PCF Retreat has concluded. To inquire about submitting a late-breaking abstract, please email [email protected].

Poster Presentation Guidelines
Each poster must be a minimum of 36′′ x 48′′ and cannot exceed 48′′ vertically x 84′′ horizontally. We will not be able to accommodate posters greater than 48′′ vertically.

The PCF Retreat Poster Session will be held on Thursday, October 23rd at 7:30 pm-10:30 pm in the Costa De La Luna Ballroom. Presenters can begin putting up their posters on Thursday at 12:00 pm. Posters should be removed by Friday at 7:00 pm. Poster board assignments are based on last name of the presenting author in alphabetical order, unless specific requests are made.

Poster Abstracts

AuthorAbstract Title
Abbas Elmahdi, AhmedUsing Machine Learning to Predict RNA Pol II Interactions of Metastatic Prostate Cancer
Acharya, BipulHuman iPSC-derived prostate organoids with germline BRCA2 mutation undergo tumorigenic transformations
Aftab, BlakeADI-212: A next-generation gene-edited and armored allogeneic CAR γδ T cell therapy targeting PSMA for prostate cancer
Agarwal, NeerajReal-world treatment patterns in patients with metastatic castration-resistant prostate cancer (mCRPC) previously treated with androgen receptor pathway inhibitor (ARPI) or docetaxel

ProstACT Global: A phase 3 study of Lutetium (Lu177) rosopatamab tetraxetan plus standard of care vs standard of care alone in patients with metastatic castration-resistant prostate cancer
Akamatsu, ShusukeTransdifferentiation of prostate adenocarcinoma to carcinosarcoma
Al Hussein Al Awamlh, BashirHealth Literacy in Prostate Cancer
Askary, AmjadResolving Cellular and Metabolic Heterogeneity of Liver mCRPC with Single-Cell Spatial Transcriptomics
Au, Cheuk Man CherieMolecular Glue Degraders of AR/AR-V7: A Paradigm Shift in the Treatment of Advanced Prostate Cancer
Bakht, MartinThe SHAPE Cohort: Integrated Genomic and Spatial Profiling of Advanced Prostate Cancer With and Without Lu-PSMA Treatment
Bellows, EleanorEpitranscriptomic reprogramming and enzalutamide resistance in prostate cancer
Blinka, StevenSPEN mutations as a biomarker for androgen receptor signaling inhibitor therapy resistance in metastatic prostate cancer
Brault, LiseDevelopment of tools to define single-cell evolution of prostate cancer metastasis under therapeutic pressure
Brown, LaKendriaVitamin D Increases Sensitivity to Radiotherapy in Advanced Metastatic African American Prostate Cancer Cell Lines
Burnham, LeanneSpatially Resolved HER2 and AR in Prostate Cancer Highlight HER2 as a Distinct Therapeutic Target
Buteau, JamesCombined Radium-223 and Lutetium-177 PSMA-I&T in patients with metastatic castration-resistant prostate cancer: first analysis of the single-center phase I/II AlphaBet trial 
Cackowski, FrankSingle Cell Analysis Reveals Upregulation of Immune Stimulatory Pathways in Quiescent Metastatic Castration Resistant Prostate Cancer Cells
Casanova-Salas, IreneIntegrated ctDNA and EV-RNA analysis uncovers tumor evolution and lineage plasticity in metastatic Prostate Cancer
Chan, Chung YingPreclinical evaluation of 68Ga/177Lu-KK02, a theranostic targeting PARP for PARP-expressing cancers
Chaudagar, KiranjTherapeutic vulnerability of prostate cancer to VPAC antagonism
Chu, CarissaFACS-based Whole-genome CRISPRi Screen to Uncover STEAP1 Regulators in Prostate Cancer
Cole, AlexanderROADMAP: Hospital and Physician Characteristics Associated with Imaging, Genetic Testing and Molecular Diagnostics
Cooper, AaronPreclinical development of AB-3028, a programmable circuit CAR T cell product intended for the treatment of metastatic castration-resistant prostate cancer (mCRPC)
Cooperberg, MatthewThe practice of active surveillance for prostate cancer: trends, variation, and quality within a large national health system
Darst, BurcuHSD3B1 (1245A>C) germline variant and prostate cancer progression in low- and favorable intermediate-risk patients
de la Calle, ClaireUse of the Prostate Health Index in Predicting Adverse Oncologic Outcomes on Active Surveillance
Dee, Edward ChristopherNational Cancer System Characteristics and Prostate Cancer Outcomes: An Analysis of Global Data
Dias, MikhailMapping the targetable proteome of metastatic castration-resistant prostate cancer
Diaz, JohnnyNew approach to model genetically defined hormone-naïve castration-sensitive human prostate cancer
Ding, Chien-KuangArtificial Intelligence-based Detection of Neuroendocrine Carcinoma of Prostate in Metastatic Biopsies
Dornisch, AnnaSpecificity of a Polygenic Score for Aggressive Prostate Cancer
Drake, JustinA liquid biopsy-based targeted proteomic assay to identify actionable targets for late-stage prostate cancer
Einstein, DavidNational Cancer Institute’s Working Group on Biochemically Recurrent Prostate Cancer: Clinical Trial Design Considerations
Elkenawi, AsmaaMapping Mitochondrial interaction in prostate Cancer
Eltit Guersetti, FelipeProteomics Analysis to Characterize Prostate Cancer Bone Metastases Subtypes
Fallatah, ArwaDiscern the Impact of Cryptochrome 1 (CRY1) on Metabolic Rewiring in PCa
Flanagan, SineadA Low Insulinemic Diet and Lifestyle for the Primary Prevention of Aggressive Prostate Cancer with PTEN Loss.
Fletcher, ClaireA MicroRNA Approach to Directly Induce Potent DNA Damage in Transcriptionally-Hyperactive Prostate Cancer Cells, and Delivery via Biocompatible ‘Nanogels’
Fonseca, NicoletteCirculating tumour DNA (ctDNA) based detection of genetic immune escape in advanced prostate cancer (aPCa)
Freeman, MichaelONECUT2 reprograms the AR network and activates non-canonical EZH2 in aggressive prostate cancer
Freeman, MichaelONECUT2 as a Central Regulator of Neuroendocrine Fate and Immune Silencing in Small Cell Lung Cancer
George, DanielDisparities in Prostate-Specific Membrane Antigen (PSMA)-Targeted Imaging Utilization Among Patients With Advanced Prostate Cancer (PC)
Godolphin, PeterEffects of prostate radiotherapy (RT) on synchronous, metastatic, hormone-sensitive prostate cancer (mHSPC): STOPCAP meta-analysis of individual participant data (IPD)
Gong, JunA nationwide VA study on first-line systemic treatment patterns in Black men with metastatic castration-resistant prostate cancer
Grist, EmilyTumor transcriptome-wide expression classifiers predict treatment sensitivity in advanced prostate cancers
Grunberg, NilCommunication between prostate tumours and peri-prostatic adipose drives obesity-associated prostate cancer aggressivity
Gueron, GeraldineTargeting Glycolysis and Mitochondrial Function in Prostate Cancer with Carbon Monoxide Releasing Molecules
Guilbault, DenisePhase 3 study of 68Ga-PSMA-11 PET combined with MRI for the detection of prostate cancer (BIPASS)
Haas, RoniJoint Biochemical & Genetic Prostate Cancer Risk Stratification
Hayes, VanessaHEROIC Prostate Cancer Precision Health Africa1K: updates from the Genomics & Data Science Working Group
Hossain, Md NiamatThe αVβ3 integrin/NgR2 complex is upregulated in NEPrCa and is a novel therapeutic target
Hsiung, ChrisEngineered CRISPR-Cas12a for combinatorial functional genomics in prostate cancer
Hsu, SarahDissecting tumor cell state heterogeneity in advanced prostate cancer
Jamaspishvili, TamaraArtificial Intelligence (AI)-Driven Quantification of p53 Expression Improves Prognostic Stratification in Prostate Cancer
Jamieson, ChristinaTherapeutic development of ULK1/2 inhibitors as adjuvant therapy in bone metastatic prostate cancer
Jarrard, DavidHistone-Modifying Enzymes in Androgen-Deprived Prostate Cancer: EZH1 as a Synergistic Therapeutic Target
Kensler, KevinTrends in GLP-1 receptor agonist use among men with prostate cancer
Kalac, MatkoFinal overall survival (OS) with talazoparib plus enzalutamide as first-line treatment in patients with homologous recombination repair (HRR)-deficient metastatic castration-resistant prostate cancer (mCRPC) in the Phase 3 TALAPRO-2 trial
Kang, Dong-WooEffects of Exercise on Cardiometabolic and Immunological Biomarkers in Men with Prostate Cancer on Active Surveillance: Findings from the ERASE Randomized Controlled Trial
Kimmel, BlaisePotentiating cancer immunotherapies with modular albumin-hitchhiking nanobody–STING agonist conjugates
Kosoff, DavidScreening of primary cancer-associated fibroblast drug sensitivity to guide rational design of cancer-associated fibroblast-targeted antibody-drug conjugates in prostate cancer
Kotula, LeszekABI1 as liquid biopsy biomarker of ARPI resistance
Kregel, StevenSOX2 utilizes FOXA1 as a heteromeric transcriptional partner to drive proliferation in therapy-resistant prostate cancer
Ku, AnsonClub-like cells and PIGR expression are associated with inflammatory high-risk, localized prostate cancer
Kumar, RajendraTargeting GPX4 to enhance ferroptosis in supraphysiologic androgen-treated prostate cancer.
Kwon, DanielEvaluating an Artificial Intelligence (AI) Communication Platform for Racial Biases in Information Quality about Prostate Cancer (PCa) Germline Testing
Labanca, EstefaniaTargeting Ketone Body Metabolism in Advanced Treatment-Resistant Prostate Cancer
Labbé, DavidPrecision nutrition to potentiate radiotherapy
Laird, DouglasExploratory analyses of homologous recombination repair alterations (HRRm) by gene subgroup and potential associations with efficacy in the HRR-deficient population from TALAPRO-2
Lallous, NadaAndrogen Receptor Variant 7 (AR-V7) Condensates Promote Growth and Proliferation in Castration-Resistant Prostate Cancer
Leiter, AmandaDiabetes Increases Cardiovascular Mortality but Not Prostate Cancer Mortality Among Men Receiving Androgen Deprivation Therapy
Li, ChennanA novel metastatic prostate cancer model from an African American man with small-cell characteristics
Li, HaolongTargeting the PTGES3-AR axis in Advanced Prostate Cancer
Lin, NeilModeling of Drug Synergies in AR-Resistant Prostate Cancer Using a Digital Twin
Link, CharlesClinical Activity and Safety of SYNC-T Therapy SV-102 in Patients with Metastatic Prostate Cancer 
Loeb, StacyBarriers and Facilitators to Lifestyle Modification in Prostate Cancer
Lyu, AramDissecting myeloid-driven mechanisms of immunotherapy resistance in prostate cancer bone metastases
Macarro, CarlosDeep Learning for Prostate Cancer BRCA Mutation Detection and Phenotypic Characterization from Histopathology
Madan, RaviProspective Monitoring of Prostate Specific Membrane Antigen (PSMA) in Biochemically Recurrent Prostate Cancer (BCR):  Preliminary Data from 1 Year Follow-up
Mahajan, KiranTargeting HOXB13 Mediated Immune Suppression of Castration-Resistant Prostate Cancers
Mahajan, NupamPhase 1 First in man Trial of Novel ACK1 Inhibitor (R)-9b in Patients with Prostate Cancer
Maher, ChristopherMethylation signature to distinguish indolent and aggressive prostate cancer
Mao, ZhiyuanTuning TCR Immunotherapy Targeting Prostatic Acid Phosphatase via Catchbond Modifications for Advanced Prostate Cancer
Mehraj, UmarTargeting NUAK2 disrupts pre-mRNA splicing and inhibits neuroendocrine prostate cancer
Mir, NabielTolerability and the Accelerome: Wrist-Worn Open-Source Accelerometry Tracks Symptom Burden in Androgen-Ablated Older Men with Metastatic Prostate Cancer
Moran, AmyThe androgen receptor tunes CD8+ T cell effector and memory responses to acute infection
Morrissey, ColmThe Continued Relevance of the Seed and Soil Hypothesis to Metastatic tumor Dissemination, Distribution, and Therapy Resistance with an Emphasis on Liver Metastasis in Castration-Resistant Prostate Cancer
Murad, JohnOptimization of Safe and Effective PSCA-CAR/IL12 Engineered T cell Combinatorial Treatment Strategies Against Metastatic Prostate Cancer
Nelson, ColleenNovel therapeutic development for aggressive variant prostate cancer
Newman, LaurenUnlocking the potential of large oncosomes as a liquid biopsy tool for prostate cancer through next generation capture and detection methods
Pacheco, Nicollette64Cu-SAR-bisPSMA PET/CT and SOC PSMA PET/CT in Biochemical Recurrence of Prostate Cancer: A Close-Up of the Phase II COBRA Trial
Pachynski, RussellChemerin augments antitumor immunity in prostate cancer via enhanced antigen presentation and NK/CD8⁺ T cell recruitment
Pandey, ApurvaConditionally activated membrane binding probes for improved targeted radiotherapy
Papachristodoulou, AlexEstablishment of pre-clinical models for the discovery of new mitochondrial biomarkers of high-risk prostate cancer
Patel, DhirenATNM-400, a first-in-class Actinium-225 antibody radioconjugate, demonstrates potent anti-tumor activity and overcomes resistance to enzalutamide and 177Lu-PSMA-617 in prostate cancer models
Patel, HitenNot in Plain Sight: Identifying Pathological Features of MRI Invisible Prostate Cancer
Patel, KrishnanTranscriptomic-Clinical Risk Stratification to Guide Abiraterone Treatment Intensification in High-Risk Prostate Cancer: A Combined Analysis of NRG/RTOG 9202, 9413, 9902, and 0521
Patnaik, AkashSpatially organized lymphocytic microenvironments in high-grade primary prostate cancer
Patnaik, AkashAndrogen receptor blockade primes NLRP3 in tumor-associated macrophages to enhance NLRP3 agonist-mediated phagocytosis and tumor control
Pattabiraman, DiwakarDiscovery of Helicon Peptides for the Selective Degradation of the Agonist-Bound Conformation of Androgen Receptor (ARon) in Prostate Cancer
Patton, RobertA deep learning framework for predicting gene expression from cell-free DNA
Poluben, LarysaEnhancing Androgen Receptor Antagonist-Mediated Interferon Responses in Prostate Cancer
Punnen, SanojEvaluation of AI-based and Genomic Prognostic Markers for the Prediction of Grade Progression in the Prostate Cancer Active Surveillance Setting
Quigley, DavidSingle-Cell Multi-Omics Reveals the Molecular Landscape and Heterogeneity of Metastatic Castration-Resistant Prostate Cancer
Rajendran, RithikaHER2-Targeted Therapy in Metastatic Castration-Resistant Prostate Cancer: Phase II Trial in Progress and Case Report of Abiraterone Re-challenge with Trastuzumab Deruxtecan 
Rajendran, RithikaCharacterization of HER2 Expression in Prostate Cancer Compared with Other Solid Tumors
Robert-Tissot, CelineReal World Evidence Reveals Sustained Androgen Receptor (AR) Expression and Activity As Resistance Mechanism to AR Signaling Inhibitors in Metastatic Castration-Resistant Prostate Cancer
Rojo Domingo, MariluzRefining Risk Stratification in Grade Group 2 Prostate Cancer: The Role of Multiparametric MRI in Detecting Cribriform and Intraductal Carcinoma
Romero, RodrigoElucidating Drivers of Neuroendocrine Plasticity in Mouse Models of Prostate Cancer
Rosen, DanielDetection and Targeting of Genomic Fusion Derived pMHC Neoantigens in Prostate Cancer
Sabbagh, AliDevelopment and external validation of a computational approach for early read out of randomized clinical trials in metastatic prostate cancer
Sachdeva, AshwinMajor Adverse Cardiovascular Events in high risk localised and metastatic hormone sensitive prostate cancer in four phase III STAMPEDE platform protocol trials
Sanchis, PabloBone-derived signals activate PKA and promote resistance to AR-targeted therapies in prostate cancer.
Sanin, DavidMyeloid Cell Regulation in Patients with Advanced Prostate Cancer treated with Bipolar Androgen Therapy
Scheinberg, TahliaPlasma lipidomics and PCPro as prognostic biomarkers in TheraP (ANZUP 1603): a randomised trial of [177Lu]Lu-PSMA-617 (LuPSMA) vs cabazitaxel in metastatic castration resistant prostate cancer (mCRPC)
Schmidt, DanielTargeting Pyruvate Kinase to Induce Metabolic Dependencies in Prostate Cancer
Schoen, MartinA novel tumor genomic classification system accurately stratifies patients with metastatic prostate cancer into distinct prognostic groups
Scurll, JoshuaThe genomic-transcriptomic landscape of high-risk localized prostate cancer in the Genomic Umbrella Neoadjuvant Study 
Sena, LauraIDH1 and IDH2 mutations in prostate cancer
Sharifi, MarinaClinical impact of high-risk genomic mutations and prostate cancer lineage state identified through high purity circulating tumor cell RNA sequencing in patients with metastatic prostate cancer
Sharma, KomalMachine Learning-based Detection of Concurrent DNA Repair Deficiencies as Dynamic Biomarkers for Prostate Cancer Precision Medicine
Shibata, MahoDerepression of endogenous retroviral elements promotes extracellular matrix remodeling and immune cell evasion in prostate cancer
Shobaki, NourAn All-in-One ‘Living Drug’ CAR T Cell Platform for Safe and Effective Targeting of Metastatic Castration-Resistant Prostate Cancer
Sim, WoogwangUncovering Compensatory Innate Immune Checkpoints to Target Aggressive Variant Prostate Cancer
Sirohi, DeepikaCorrelation of Canary Histological Patterns at Radical Prostatectomy with Decipher GRID Basal and Luminal Signature Score.
Sirohi, DeepikaValidation of Canary Histological Patterns at Radical Prostatectomy with Decipher GRID Prognosis Signature Score 
Sjöström, MartinNon-invasive prostate cancer subtyping using 5hmC-sequencing of cell-free DNA
Soh, PamelaProstate cancer genetic risk in Africa: evaluating polygenic risk scores and germline testing
Sokolova, AlexandraTRIPLE-SWITCH(SWOG/CCTG-PR26): Randomized Phase III Clinical Trial of Docetaxel with Androgen Receptor Pathway Inhibitors for Metastatic Castration-Sensitive Prostate Cancer Patients with a Suboptimal PSA Response
Stoyanova, TanyaExtracellular Domain Shedding of TROP2 Activates EGFR Signaling to Drive Prostate Cancer Metastasis
Subudhi, SumitThe Path Forward for CD28-Targeted T Cell Engagers in Prostate Cancer
Sumiyoshi, TakayukiTranscriptome analysis of de novo metastatic castration-sensitive prostate cancer using long-read sequencing technologies
Sutera, PhilipEvaluating associations between genomic classifier and digital pathology based multi-modal AI biomarkers in localized and metastatic prostate cancer
Takeda, DavidMechanism of AR enhancer activation in castration-resistant prostate cancer
Tendler, SalomonActinium-225 Radioimmunotherapy in Delta-like Ligand 3 NEPC tumor model
Tolmeijer, SofieBlood and imaging response correlatives in advanced prostate cancer treated with combination radioligand and immunotherapy
Trock, BrucePhysical Activity and Risk of Prostate Cancer Grade Reclassification on Active Surveillance: Results from a Prospective Cohort Study
Tsao, PhoebeImpact of androgen receptor pathway inhibitors on mental health in Veterans with metastatic hormone-sensitive prostate cancer
Venkadakrishnan, Varadha BalajiModulation Of Chromatin Bivalency Facilitates Prostate Cancer Lineage Plasticity
Wala, JeremiahSpatially organized lymphocytic microenvironments in high grade primary prostate tumors
Wang, ZhipengRoles, Regulations, and Therapeutic Potential of the Lysine Acetoacetylome in Prostate Cancer
Washington III, SamuelHeterogeneity of community drivers of social vulnerability across racial groups of men with prostate cancer
Weiner, AdamMolecular Characterization of Imaging-Invisible Prostate Tumors
Weller, SarahImproving prostate cancer outcomes globally: A Movember update
Wurzer, AlexanderA preclinical evaluation on the radiohybrid tandem [18F]La- and [225Ac]Ac-rhPSMA-10.1 for targeted alpha therapy of prostate cancer
Wyatt, AlexCDK12 is a prostate cancer predisposition gene
Xu, GeorgePredicting Active Surveillance Failure in the Magnetic Resonance Imaging Era: A Multicentre Transatlantic Cohort Study
Xu, PingLongitudinal Profiling of Circulating Tumor DNA Reveals the Evolutionary Dynamics of Metastatic Prostate Cancer during Serial Therapy
Xu, XinRNA Epitranscriptomic editing Screening Identifies Functional m6A Sites in Prostate Cancer
Ye, HuihuiMitochondrial Metabolic Reprogramming Orchestrates Tumor–Immune Crosstalk and Dictates Disease Outcomes in Primary Prostate Cancer
Younger, NoahIdentification and characterization of PLUTO-201, a novel lncRNA associated with prostate cancer metastasis
Zhao, DiHistone Methyltransferase ASH1L Primes Metastases and Metabolic Reprogramming of Macrophages in the Bone Niche
Zhao, FamingDeciphering single-cell heterogeneity and cellular ecosystem dynamics during prostate cancer progression
Zhu, XiaolinTargeting SSTR1 to overcome resistance to androgen receptor signaling inhibition in prostate cancer
Zorko, NicholasDetermining Optimal NK Cell Features for Immune Engagement with Tri-specific Killer Engager Molecules