Challenge Awards Class of 2023
2023 PCF Challenge Award
Modulation of Anti-Androgen Response by NSD2 in Castration-Resistant Prostate Cancer
Principal Investigators: Michael Shen, PhD (Columbia University Medical Center), Andrea Califano, PhD (Columbia University Medical Center), Johann de Bono, MD, PhD (The Institute of Cancer Research), Charles L. Sawyers, MD (Memorial Sloan Kettering Cancer Center)
Young Investigators: Jia Li, PhD (Columbia University Medical Center), Zhen Sun, PhD (Memorial Sloan Kettering Cancer Center), Alessandro Vasciaveo, PhD (Columbia University Medical Center)
Collaborators: Cory Abate-Shen, PhD (Columbia University Medical Center), Kristian Helin, PhD (The Institute of Cancer Research Cancer), Massimo Loda, MD (Weill Cornell Medicine), Chao Lu, PhD (Columbia University Medical Center)
2023 Bayer-PCF Darolutamide Challenge Award
Darostep: Evaluating Step Counts as a Biomarker and its Relationship on Treatment Outcomes in Vulnerable Patients with Metastatic Hormone-Sensitive Prostate Cancer on Darolutamide and Androgen Deprivation Therapy
Principal Investigators: Russell Szmulewitz, MD (The University of Chicago), Nabiel Mir, MBBS (The University of Chicago), Megan Huisingh-Scheetz, MPH, MD (The University of Chicago)
2023 Movember, Todd Boehly, Shmuel Meitar, Richard Merkin, MD, Marcel Claure-PCF Challenge Award
Identification of Patients at High-Risk of Metastatic Disease after Neoadjuvant Intensive Androgen Signaling Inhibition
Principal Investigators: Mary-Ellen Taplin, MD (Dana-Farber Cancer Institute), Steven Balk, MD, PhD (Beth Israel Deaconess Medical Center)
Young Investigators: Praful Ravi, MD (Dana-Farber Cancer Institute), Joshua Russo, MD, PhD (Beth Israel Deaconess Medical Center), Zijun Frank Zhang, PhD (Cedars-Sinai Medical Center)
Co-Investigators: Eliezer Van Allen, MD (Dana-Farber Cancer Institute), Corey Arnold, PhD (University of California at Los Angeles), Huihui Ye, MD (Cedars-Sinai Medical Center), Stephanie Harmon, PhD (National Cancer Institute), Adam Sowalsky, PhD (National Cancer Institute)
2023 Igor Tulchinsky-PCF Challenge Award
ctDNA Determinants of Resistance to 177Lu-PSMA-617 versus Taxane-Based Chemotherapy
Principal Investigators: Alexander Wyatt, PhD (Vancouver Prostate Centre), Arun Azad, MD (Peter MacCallum Cancer), Kim Chi, MD (BC Cancer), Michael Hofman, MBBS (Peter MacCallum Cancer Centre)
Young Investigators: Heidi Fettke, PhD (Peter MacCallum Cancer Centre), Edmond Kwan, MBBS, PhD (University of British Columbia), Corinne Maurice-Dror, MD (BC Cancer), Martin Sjostrom, MD, PhD (University of California San Francisco)
Co-Investigators: Fred Saad, MD (University of Montreal Hospital Center), Francois Bernard, MD (BC Cancer), Ian Davis, MBBS, PhD (Monash University), Matti Annala, BS (Tampere University), Felix Feng, MD (University of California, San Francisco), Wendy Parulekar, MD (Queen’s University)
2023 Richard Solomon, Igor Tulchinsky, Darius Bikoff, John Paulson, Richard Sandler, Bill Mack, Jason Safriet-PCF Challenge Award
New Targeted Epigenetic Therapy for Androgen Receptor-Negative Prostate Cancer
Principal Investigators: Ming-Ming Zhou, PhD (Icahn School of Medicine at Mount Sinai), Kunhong Xiao, MD, PhD (Allegheny Health Network Cancer Institute)
Young Investigator: Zuqiang Liu, PhD (Allegheny Health Network Cancer Institute)
Collaborators: Bharath Kumar Gajjela, PhD (Icahn School of Medicine at Mount Sinai), Michael Appiah, PhD (Icahn School of Medicine at Mount Sinai), Anurupa Ghosh, PhD (Icahn School of Medicine at Mount Sinai), Qiangmin Zhang, PhD (Allegheny Health Network Cancer Institute), Xi Peng, PhD (Allegheny Health Network Cancer Institute), Yunxiang Fu, BA (Allegheny Health Network Cancer Institute), David Bartlett, MD (Allegheny Health Network Cancer Institute)