Collection of Blood From Patients With Cancer
Biospecimen Acquisition From Human Subjects
About This Trial
- This study is open to adults with cancer, including prostate cancer, who want to help researchers better understand the immune system.
- Researchers are collecting small blood samples to see how certain immune cells behave before and after cancer therapies.
- It is important to know that this study does not provide any cancer treatment and will not replace your regular medical care.
- Participation simply involves having a few tablespoons of blood drawn, though you may be offered the chance to join other treatment studies in the future.
More Information
- This study will collect blood from patients with cancer to study the level of cells which decrease the immune response (suppressor cells) before and after chemotherapy.
- Patients 18 years of age and older with cancer may participate.
- This study does not involve treatment.
- Participants will have about 50 ml (3 tablespoonfuls) of blood drawn.
- Depending on their condition, patients may be invited to enroll in a clinical research study involving chemotherapy, radiotherapy, or surgery.
- Additional 40-ml blood samples may be drawn during the course of treatment.
Who Can Enroll
- Age Range: 18 years and older
- Gender: All
- Who This Trial is For: This study is open to adults with cancer, including prostate cancer, who want to help researchers better understand the immune system.
Study Details
- Start Date: July 16, 2002
- Lead Sponsor: National Cancer Institute (NCI)
Full Eligibility Criteria
Inclusion Criteria
Patients with a known or suspected malignancy and healthy volunteers 18 years of age and
older are eligible.
Performance status of ECOG 0, 1, 2, or 3 for admission to this protocol.
Ability to understand and the willingness to sign a written informed consent document.
INCLUSION FOR APHERESIS:
Note: Effective with Amendment CC, participants will no longer be asked to undergo
apheresis. This content is being retained for historical reference.
Hemoglobin greater than or equal to 10 mg/dL and platelet count > 75,000/mm(3)
Weight greater than 25 kg
HIV negative
Prothrombin Time - within normal limits
Partial Thromboplastin Time - within normal limits
Medically indicated central line in place or adequate peripheral venous access
Exclusion Criteria
None.