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TACTICAL Awards- Class of 2022

The PCF TACTICAL Award-Class of 2022 recipients are:


Project Title: An Accelerated Platform using Lead-212 Targeted α-particle Therapy to Radically Improve Cancer Lethality of Prostate Cancer Theranostics using Novel Targets and Better Understanding of Resistance: the Cancer Lethality Lead Collaboration

Principal Investigators: Michael Hofman, MBBS (Peter MacCallum Cancer Centre), Mohammad Haskali, PhD (Peter MacCallum Cancer Centre), Luc Furic, PhD (Peter MacCallum Cancer Centre), Johannes Czernin, MD (University of California, Los Angeles), Christine Mona, PhD (University of California, Los Angeles), Caius Radu, MD (University of California, Los Angeles), Tom Hope, MD (University of California, San Francisco), Felix Feng, MD (University of California, San Francisco), Ken Herrmann, MD (Uniklinik Essen), Katharina Lückerath, PhD (Uniklinik Essen), Heidi Fettke, PhD (Peter MacCallum Cancer Centre), Elie Besserer, PhD (University of California, Los Angeles), Martin Sjoestroem, MD, PhD (University of California, San Francisco), Valeska von Kiedrowski, PhD (Uniklinik Essen)

Co-Investigators: Shahneen Sandhu, MBBS (Peter MacCallum Cancer Centre), Anna Trigos, PhD (Peter MacCallum Cancer Centre), Arun Azad, MD, PhD (Peter MacCallum Cancer Centre), Declan Murphy, FRACS (Peter MacCallum Cancer Centre), Giuseppe Carlucci, PhD (University of California, Los Angeles), Thuc Le, PhD (University of California, Los Angeles), Jonathan Tranel, PhD (University of California, San Francisco), Wolfgang Fendler, MD (Uniklinik Essen), Anna Pacelli, PhD (Uniklinik Essen)

Young Investigators: Marwa Rahimi, PhD (Peter MacCallum Cancer Centre), Magdalena Staniszewska, PhD (Uniklinik Essen)

View project description here.


Project Title: Developing Engineered Cell Therapies for Metastatic Castrate-Resistant Prostate Cancer to Increase Efficacy and Decrease Toxicity

Principal Investigators: Carl June, MD (University of Pennsylvania), Saul Priceman, PhD (City of Hope), Joseph Fraietta, PhD (University of Pennsylvania), Naomi Haas, MD (Abramson Cancer Center at the University of Pennsylvania Perelman School of Medicine), Avery Posey, PhD (University of Pennsylvania), Tanya Dorff, MD (City of Hope), John Maris, MD (Children’s Hospital of Philadelphia), James Gulley, MD, PhD (National Cancer Institute)

Co-Investigators: Vivek Narayan, MD (Abramson Cancer Center at the University of Pennsylvania Perelman School of Medicine), Priti Lal, MD (University of Pennsylvania), Regina Young, PhD (University of Pennsylvania), Evan Weber, PhD (Children’s Hospital of Philadelphia), Yi Xing, PhD (Children’s Hospital of Philadelphia), Nikolaous Sgourakis, PhD (Children’s Hospital of Philadelphia), Peter Choyke, MD (National Cancer Institute), Scott Norberg, DO (National Cancer Institute), Wiem Lassoued, PhD (National Cancer Institute), Jennifer Marte, MD, MPH (National Cancer Institute), Nan-Ping Weng, MD, PhD (National Institute on Aging), Peter Kuhn, PhD (University of Southern California), Kara Maxwell, MD, PhD (The Corporal Michael J. Crescenz VA Medical Center), Daniel Lee, MD (The Corporal Michael J. Crescenz VA Medical Center), Darshana Jhala, MD (The Corporal Michael J. Crescenz VA Medical Center)

Young Investigators: Andrew Rech, MD, PhD (University of Pennsylvania), Mark Yarmarkovich, PhD (Children’s Hospital of Philadelphia)

View project description here.


Project Title: Novel Theranostic Agents for Neuroendocrine Prostate Cancer

Principal Investigators: Jason Lewis, PhD (Memorial Sloan Kettering Cancer Center), Michael Morris, MD (Memorial Sloan Kettering Cancer Center), Lisa Bodei, MD, PhD (Memorial Sloan Kettering Cancer Center), Himisha Beltran, MD (Dana-Farber Cancer Institute), Felix Feng, MD (University of California San Francisco), Samir Zaidi, MD, PhD (Memorial Sloan Kettering Cancer Center), John Poirier, PhD (NYU Grossman School of Medicine)

Co-Investigators: Kishore Pillarsetty, PhD (Memorial Sloan Kettering Cancer Center), Yu Chen, MD, PhD (Memorial Sloan Kettering Cancer Center), Anuradha Gopalan, MD (Memorial Sloan Kettering Cancer Center)

Young Investigators: Ryan Reddy, MD (Memorial Sloan Kettering Cancer Center), Salomon Tendler, MD, PhD (Memorial Sloan Kettering Cancer Center), Audrey Mauguen, PhD (Memorial Sloan Kettering Cancer Center)

View project description here.


Project Title: Tactical Approaches to Repress oncogenic Gene Expression in prostatic Tumors (TARGET)

Principal Investigators: Arul Chinnaiyan, MD, PhD (University of Michigan), Sarki Abdulkadir, MD, PhD (Northwestern University)

Co-Investigators: Shaomeng Wang, PhD (University of Michigan), Ganesh Palapattu, MD (University of Michigan), Joshi Alumkal, MD (University of Michigan), Zachery Reichert, MD (University of Michigan), Ulka Vaishampayan, MD (University of Michigan), Maha Hussain, MD (Northwestern University), Gary Schiltz, PhD (Northwestern University), Yuzhuo Wang, PhD (University of British Columbia), Ke Ding, PhD (Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences), Xiaoju (George) Wang, PhD (University of Michigan), Jean Tien, PhD (University of Michigan), Yuanyuan Qiao, PhD (University of Michigan), Jeanne Stuckey, PhD (University of Michigan), Alex Tsodikov, PhD (University of Michigan), Jeremy Taylor, PhD (University of Michigan)

Young Investigators: Abhijit Parolia, PhD (University of Michigan), Lanbo Xiao, PhD (University of Michigan), Sarah Fenton, MD, PhD (Northwestern University)

View project description here.

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