The Use of Ultrasound in Assessing Post-prostatectomy Erectile Dysfunction
Ultrasound Vibroelastography in Post-Prostatectomy Erectile Dysfunction
About This Trial
- This study is testing whether a specialized, painless ultrasound can help doctors better track and understand how erectile function recovers after prostate cancer surgery.
- It is open to men over 40 with early-stage prostate cancer who currently have good erectile function and are scheduled for surgery that spares the surrounding nerves.
- Patients should know that they may not be eligible if they have already received hormone therapy, had previous pelvic surgeries, or currently have significant erectile difficulties.
More Information
- Researchers are trying to determine whether there is additional utility to using vibroelastography, a noninvasive ultrasound technique to evaluate for the presence of tissue fibrosis, in conjunction with standard penile duplex Doppler ultrasound to assess erectile function (recovery) after prostate cancer surgery.
Who Can Enroll
- Age Range: 40 years and older
- Gender: Male
- Who This Trial is For: This study is testing whether a specialized, painless ultrasound can help doctors better track and understand how erectile function recovers after prostate cancer surgery.
Study Details
- Start Date: October 2, 2023
- Lead Sponsor: Mayo Clinic
Full Eligibility Criteria
Inclusion criteria include:
- Age > 40 years
- Clinically localized prostate cancer (American Urological Association Grade Groups 1-2; cT1c or cT2a-b; PSA < 10) without clinic or imaging evidence of localized extra-prostatic or metastatic disease (i.e. AUA low and favorable intermediate risk prostate cancer)
- International Index of Erectile Function (IIEF) of ≥ 21 points at baseline (no or mild erectile dysfunction)
- Patient-expressed interest in consultation for sexual function (erectile function) preservation/ optimization
- Planned bilateral nerves-paring prostatectomy Exclusion criteria include:
- Moderate or severe ED based in IIEF criteria (score < 21)
- History of prior pelvic or penile surgery
- Current or prior androgen deprivation therapy
- Planned non-nerve sparing prostatectomy
Treatments
- Diagnostic Test: Ulrasound Vibroelastography (UVE)