About Christopher Maher
The speed of sequencing the entire DNA content of human prostate cancer has increased by more than 100 times and the cost has been decreased by over 1,000 times in the past five years. The huge amount of data generated in these studies presents challenges when researchers seek to discover the genetic alterations that cause the initiation and progression of cancer. Dr. Maher and colleagues have developed new software bioinformatic tools to extract such data from mass sequencing efforts for prostate cancer. He proposes to sequence more than 100 prostate cancer RNA profiles in an attempt to classify subsets of prostate cancer patients based on unique genetic alterations. This work will set the stage for the discovery of new targeted therapies for different “species” of advanced prostate cancers that need different treatments.
The 2010 Stewart Rahr – PCF Young Investigator Award
Christopher Maher, PhD
University of Michigan – Ann Arbor, MI
Arul Chinnaiyan, MD, PhD, Howard Hughes Medical Institute Investigator, Director of Pathology Research Informatics, Director of Cancer Bioinformatics, S.P. Hicks Endowed Professor of Pathology, American Cancer Society Research Professor, Professor of Urology, at the University of Michigan.