About Edwin Posadas
Dr. Posadas’ research goal is to identify the molecular mechanisms of prostate cancer metastasis. A protein called FYN, which is a member of a cancer-causing gene family, was identified in his laboratory as a possible regulator of metastasis. The biology of metastasis is driven by molecular changes within cancer cells that enable cell motility, which contributes to the spread of cancer throughout the body. Analysis of prostate cancer tumor specimens showed that there were higher levels of FYN in cancer cells as compared to normal cells. Dr. Posadas will comprehensively define the function of FYN in prostate cancer cells. These studies may lead to the development of novel targeted therapies that block FYN function and prevent prostate cancer metastasis and cases of advanced prostate cancer in patients.
The 2010 Stewart Rahr – PCF Young Investigator Award
Edwin Posadas, MD
Cedars-Sinai Medical Center – Los Angeles, CA
Walter Stadler, MD, Fred C. Buffett Professor, Departments of Medicine and Surgery, Director, Genitourinary Oncology and Associate Dean of Clinical Research at the University of Chicago.
Carrie Rinker-Schaeffer, PhD, Associate Professor for Surgery, Medicine and Obstetrics and Gynecology, Director of Urological Research, the University of Chicago
Ravi Salgia, MD, PhD, Professor of Medicine, Director of Thoracic Oncolgoy Research Program and Aerodigestive Tract Program Translational Research Laboratories at the University of Chicago.