Prostate Cancer Dream Challenge

The Prostate Cancer DREAM Challenge will be launching in the first quarter of 2015; this project is a collaboration with Project Data Sphere, LLC, the DREAM Project, the Prostate Cancer Foundation, and Sage Bionetworks.

The Prostate Cancer DREAM Challenge launched on March 16th and will be running through July 2015; this project is a collaboration with Project Data Sphere, LLC, the DREAM Project, the Prostate Cancer Foundation, and Sage Bionetworks. The objectives of the Challenge are to:

  • address clinically relevant research questions regarding patients with metastatic Castration Resistant Prostate Cancer (mCRPC)
  • explore innovative research/modeling approaches utilizing phase III comparator arm trial data available in the Project Data Sphere® platform

The Challenge data has been integrated from four different clinical trials with over 2,000 mCRPC patients treated with first-line docetaxel. The Challenge encourages participants to develop prognostic models that predict survival, disease progression, and toxicity of chemotherapy treatment in mCRPC patients.

This is the first crowd-sourcing computational challenge for Prostate Cancer. View the Challenge wiki and register to begin participating in the Challenge today by visiting this link: www.synapse.org/#!Synapse:syn2813558

The Project Data Sphere online service (www.projectdatasphere.org) provides one place where the cancer community can broadly share, integrate, analyze and discuss historical patient-level comparator arm data sets (historical patient-level cancer phase III) from multiple providers, with the goal of advancing cancer research. The platform currently contains over 10,000 patient lives, nearly 8,500 of which are across a wide spectrum of Prostate Cancer populations. A subset of this data will be leveraged for the Challenge.

Terms to know from this article:

Progression

Increase in the size of a tumor or spread of cancer in the body.