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07/19/2018

Genomic Landscape of Metastatic Prostate Cancer Unveiled in New Study

A comprehensive genetic analysis of metastatic prostate cancer has, for the first time, revealed a number of major ways in which abnormal alterations of the genome propel this aggressive form of the disease. As reported in the July 19, 2018 issue of Cell, a team led by investigators at UC... Read More

07/11/2018

Deadly Form of Advanced Prostate Cancer is Common, Calls for Distinct Treatment

Original article issued by UCSF News. A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer. Previously, it... Read More

07/10/2018

Tumors Grown in the Lab Provide Insights on Rare Prostate Cancer

Original article issued by Weill Cornell Medicine. Growing miniature tumors from patient’s cells in the laboratory may help scientists personalize treatments for those with a rare form of prostate cancer, according a study by Weill Cornell Medicine and NewYork-Presbyterian scientists. Patients with prostate cancer often receive therapies that reduce levels... Read More

06/26/2018

How Your Spit May Help Doctors Diagnose Prostate Cancer

Original article issued by Healthline. It might seem inconceivable that a simple saliva test can tell you your chances of developing cancer. But evidently it can. And the reason is crude but simple: Your genetic makeup can be found in your spit. Scientists are now able to extract DNA from cells... Read More

06/25/2018

Researchers find prostate cancer drug byproduct can fuel cancer cells

Original press release issued by: Cleveland Clinic. A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with... Read More

06/22/2018

Crystal Ball for Predicting Cancer Treatment Response: Your Poop?

What does the population of bacteria in your gut (called the gut “microbiome”) have to do with prostate cancer? Just how important is this gut flora, or bacteria, anyway? It’s not even in the prostate! Let’s look at the second question first. How important is your gut bacteria? It’s very... Read More

06/14/2018

New Study Identifies Another Opportunity for Precision Immunotherapy in Prostate Cancer

A new Prostate Cancer Foundation (PCF)-funded study published today in the scientific journal Cell has identified a new subtype of advanced prostate cancer – one which may be treatable with checkpoint immunotherapy, a type of treatment that can produce long-term remissions and even cures in many cancer types, but has... Read More

06/14/2018

Non-coding DNA reveals a route by which advanced prostate cancer resists treatment

More than three quarters of metastatic prostate cancers that resist hormone-blocking therapies may harbor several duplicates of both the gene for a treatment resistance factor called the androgen receptor (AR) and of a never-before-seen genetic switch, or enhancer, that boosts the gene's expression. The duplications, as well as epigenetic signs... Read More

06/07/2018

New and More Sensitive Prostate Cancer Imaging on the Near Horizon

At the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting, promising results were reported from a phase 2/3 clinical trial testing the accuracy of a new prostate cancer imaging method -- PSMA-PET -- for detecting sites of prostate cancer recurrence. The current standard imaging methods for detecting recurrent or... Read More

Why More Men Are Delaying Treatment for Prostate Cancer

Original article issued by Healthline. When Ben Pfeiffer was diagnosed with prostate cancer in April, his urologist noted in the biopsy report that he was leaning toward recommending that Pfeiffer have his prostate surgically removed. But Pfeiffer, 58, a married construction supervisor from Las Vegas with two grown daughters, said... Read More