Poster Abstracts (26th Annual)

The deadline to submit an abstract for poster presentations has passed.  To inquire about submitting a late-breaking abstract, please email [email protected].

All PCF Retreat attendees are highly encouraged to submit an abstract for a poster presentation summarizing your recent prostate cancer research. All submitted abstracts will be publicly posted on the Retreat website and PCF Retreat mobile app. Due to space restrictions, a limited number of submissions will be selected to present posters at the meeting.


ABSTRACT SUBMISSION GUIDELINES

Please upload a Microsoft Word document containing your abstract on the Registration webpage.

The font must be in Tahoma, 10pt. Please make sure all formatting and special characters are displayed properly before submission. Failure to follow formatting guidelines may result in incorrect display of your abstract.

Abstracts must include: Title, Authors, Affiliations, Background, Methods, Results, Conclusions, and Conflict of Interest and Funding Acknowledgements.

Word limit is 450 words (abstract body).


POSTER PRESENTATION INFORMATION

Each poster must be a minimum of 36″ x 48″ and cannot exceed 48″ (vertical) x 96″ (horizontal). Poster board assignments and details on poster set-up will be emailed to presenters in early October.

The Poster Session will be held on Thursday, October 24, 2019, from 8:00pm to 10:30pm. Posters will be arranged in alphabetical order by the presenting author’s last name. Copies of the poster on 11″ x 17″ paper can accompany the poster as handouts but cannot be mounted on the poster boards.

For poster presentation inquiries please contact [email protected] or (310) 570-4705.


Author Abstract Title
Adelaiye-Ogala, Remi Targeting of the PI3K/AKT pathway overcomes enzalutamide resistance by inhibiting the induction of glucocorticoid receptor
Aggarwal, Rahul Results from a Phase 1b/2a study of the BET bromodomain inhibitor ZEN-3694 in combination with enzalutamide in patients with metastatic castration-resistant prostate cancer (mCRPC)
Akamatsu, Shusuke Prospective evaluation of germline genetic testing in prostate cancer screening among Japanese.
Al Abo, Muthana Race-related LMO7 exon skipping enhances prostate tumor invasion
Aldubayan, Saud Leveraging population-specific genomic architecture to dissect rare genetic drivers of PC heritability
Amend, Sarah Polyploid giant cancer cells are actuators of therapeutic resistance and prostate cancer lethality
Armstrong, Andrew Liquid Biopsy Molecular Signatures of Hormone Therapy Resistance in Men with Metastatic CastrationResistant Prostate Cancer (mCRPC)
Asangani, Irfan CDK7 inhibition suppresses Castration-Resistant Prostate Cancer through MED1 inactivation
Asim, Mohammad ATM inhibition sensitises prostate cancer cells to PARP inhibitors
Augello, Michael CHD1 loss alters AR binding at lineage-specific enhancers and modulates distinct transcriptional programs to drive prostate tumorigenesis
Beshiri, Mike Differentiation and subpopulation dynamics of treatment-emergent neuroendocrine prostate cancer in patient-derived organoids.
Bevan, Charlotte Role of bromodomain-containing androgen receptor cofactors in prostate cancer
Bjartell, Anders PIONEER: a BD4BO (Big data for better outcome) prostate cancer project
Bjartell, Anders Harnessing the power of big data in prostate cancer research – Data access and sources in the PIONEER project
Buelow, Ben TNB-585: A Novel CD3xPSMA Bispecific Antibody for Efficient T Cell Mediated Killing of Prostate Tumor Cells with Minimal Cytokine Release
Buskin, Adriana Transforming precision medicine in lethal prostate cancer using stem cell derived organoids
Byrne, James Extremophile RNA delivery for Radioprotection in Prostate Cancer Patients
Cackowski, Frank A New Immune Competent, Androgen Receptor Positive Mouse Model of Prostate Cancer Bone Metastasis.
Calais, Jeremie Total-body 68Ga-PSMA-11 PET/CT for bone metastasis detection in prostate cancer patients:
Potential Impact on bone scan guidelines
Calcinotto, Arianna The role of microbiota in driving castration-resistant prostate cancer.
Campbell, Douglas Proposed Study Design for a Miltuximab® Phase 1 Trial 89Zr/177Lu theranostic trial
Cantor, Diego Prostate Lesion Segmentation Using a Deep Learning Ensemble
Caram, Megan Patterns of Treatment Among Veterans with Advanced Prostate Cancer
Castro, Elena Impact of germline mutations in Homologous Recombination (HR) genes on the response to Radium-223 for metastatic castration resistant prostate cancer (mCRPC)
Chakraborty, Goutam A Study on BRCA2-RB1 Co-loss, EMT and Aggressive Therapy Resistant Prostate Cancer
Chan, June Feasibility and acceptability of a web-based behavioral intervention in men with prostate cancer (PCa): a randomized pilot trial
Cheng, Michael Tumour lineage shapes BRCA-mediated phenotypes
Cherkasov, Artem Development of small molecule inhibitors targeting the N-terminal domain of human androgen receptor
Chou, Jonathan Clinical Outcomes in CDK12 Mutant Advanced Prostate Cancer
Chu, Gina Metastasis-initiating cells (MICs) recruit and reprogram bystander indolent cells to undergo lineage plasticity facilitating prostate cancer progression and metastasis
Coombs, Catherine Impact of clonal hematopoiesis mutations in solid tumor patients with a future focus for men with castration-resistant prostate cancer
Corey, Eva CRPC Tumors Are Inhibited by High Testosterone Therapy: Can We Identify Responders?
Cotter, Kellie Epitranscriptomic Gene Regulation by N6-Adenosine-Methyltransferase in Prostate Cancer
Crawford, David NEXT GENERATION SEQUENCING OF MICROBIOMES IN POST-DRE URINE SAMPLES OF PROSTATE CANCER PATIENTS
Damayanti, Nur Targeting androgen receptor phosphorylation to overcome enzalutamide resistance in advance prostate cancer
Davies, Alastair Epigenetic reprogramming of AR function underlies lineage infidelity in advanced prostate cancer
de Leeuw, Renee Phosphatase deregulation in prostate cancer progression
De Sarkar, Navonil iHRD Classification Framework for mCRPC: An Efficient Response Predictor for Precision Therapeutics Targeting DNA Repair Defect
Diaz-Meco, Maria Metabolic vulnerabilities in therapy resistance in prostate cancer
Dondossola, Eleonora Radium 223-mediates zonal cytotoxicity of prostate cancer in bone
Drake, Justin RET Kinase as a Driver of Neuroendocrine Prostate Cancer
Einstein, David Identifying and Targeting Immunogenic Prostate Cancer at High Risk for Lethal Metastatic Progression
Flavell, Robert Hyperpolarized interstitial pH imaging reveals grade dependent acidification in prostate cancer
Fletcher, Claire MIR-346 INTERACTION WITH LONG NON-CODING RNA, NORAD, REVEALS A NOVEL GENOME PROTECTION MECHANISM AND MODULATES RESPONSE TO DNA-DAMAGING THERAPEUTICS IN ADVANCED PROSTATE CANCER
Gao, Dong Single-cell transcriptomics identifies a prostate luminal progenitor cell
Gao, Dong ERG orchestrates chromatin interactions driving prostate cell fate reprogramming
George, Daniel First 500 Patients of IRONMAN: International Registry for Men with Advanced Prostate Cancer
Giacobbe, Arianna Investigating the heterogeneity of circulating tumor cells in a mouse model of metastatic prostate cancer
Giancotti, Filiippo The Polycomb Repressor Complex 1 Drives DoubleNegative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
Gueron, Geraldine Integrative tissue “omics” reveals a biomarker gene signature that re-defines prostate cancer risk for Gleason Score 6 & 7
Ha, Gavin Multi-omic profiling of circulating tumor DNA in patients with CRPC
Hamid, Anis Genomic predictors of benefit of docetaxel (D) and next-generation hormonal therapy (NHT) in metastatic castration resistant prostate cancer (mCRPC)
Harmon, Stephanie Deep Learning approach for classification of prostate cancer morphology features on whole mount digital pathology specimens
He, Housheng The expression, function and clinical implication of circular RNAs in prostate cancer
Heaphy, Christopher Telomere lengths differ significantly between small cell neuroendocrine carcinoma and adenocarcinoma of the prostate
Hebert-DeRouen, Mindy Neighborhoods archetypes for understanding disparities in prostate cancer mortality
Hectors, Stefanie Luminal water imaging of prostate cancer: quantitative comparison with diffusion-weighted imaging for characterization of cancer aggressiveness
Hua, Junjie Risk SNP-mediated bifunctional regulatory element drives prostate cancer through lncRNA PCAT19
Jamieson, Christina Targeting the WNT5A Receptor, ROR1, in Prostate Cancer
Jayaram, Anuradha Plasma gene conversions after 1 cycle abiraterone acetate(AA) for metastatic castrationresistant prostate cancer (mCRPC): a biomarker analysis of a multi-centre, international trial
Jo, Janggun Evaluating Prostate Cancer by Functional Photoacoustic Imaging with Nanoprobe
Jones, Jennifer Development of a Pipeline for Analysis of Extracellular Vesicles in Health and Disease
Joshua, Anthony The effect of Metformin and Statin in Men with Biochemically Recurrent Prostate Cancer (BCRPC) – A single-centre retrospective study
Kaldjian, Eric Investigation of circulating tumor cells using RarePlex® Developer assays for custom biomarkers and validation of the RarePlex AR-V7 assay
Kaochar, Salma TARGETING THE PI3K/Akt/mTOR/SREBP1 SIGNALING AXIS IN CASTRATION RESISTANT PROSTATE CANCER
Karthaus, Wouter Identifying novel regulators of lineage plasticity in an organoid model of transdifferentiation.
Kenfield, Stacey Feasibility of a remote-based exercise pilot randomized controlled trial in men with metastatic castration-resistant prostate cancer: research in progress from the CHAMP study
Kishan, Amar Association of Black Race with Improved Outcomes Following Definitive Radiotherapy with Androgen Deprivation Therapy in Localized Prostate Cancer: An Individual Patient Data Meta-Analysis of Eight Randomized Trials
Kregel, Steven A novel model of prostate cancer suggests enzalutamide functions through the immune system to diminish castration resistant and metastatic growth
Ku, Sheng-Yu Loss of Notch signaling facilitates neuroendocrine differentiation in advanced prostate cancer
Kuhn, Peter Genomic Characterization of Circulating Tumor Cells in De Novo Metastatic Prostate Cancer
Labbe, David High-fat diet-dependent activation of the DNA damage response as an underlying mechanism of prostate cancer aggressiveness
Lack, Nathan Functional characterization of androgen receptor mediated transcription
Le Moigne, Ronan EPI-7386 is a novel N-terminal domain androgen receptor inhibitor for the treatment of prostate cancer
Leach, Damien The role of the microenvironment in therapeutic response to anti-prostate cancer treatment.
Lee, John CUDC-907, a dual PI3K and HDAC inhibitor, with broad activity against castration-resistant prostate cancer
Lee, Wen-Yee Urinary Volatile Organic Compounds (VOCs) for the diagnosis of Prostate Cancer
Li, Hui Investigating the Role of The Long Noncoding RNA SChLAP1-AS in Prostate Cancer Progression
Li, Wenliang Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers
Liu, Deli Impact of distinct tumor lineage models on prostate cancer prognosis
Loeb, Stacy Quality and Diversity of Information About Prostate Cancer Clinical Trials on YouTube
Lorenzin, Francesca Dependencies of CRPC cell fitness on ERG levels
Lu, Xin Myeloid-Derived Suppressor Cells Inhibit T Cell Activation in Prostate Cancer through Nitrating LCK
Madan, Ravi ChemoImmunotherapy for the Treatment of Metastatic Prostate Cancer
Mahajan, Kiran CIT kinase and HSPB8 as Novel Biomarkers for Identification of Metastatic Prostate Cancers
Mahajan, Nupam A novel therapeutic agent (R)-9bMS for treatment of Castration Resistant Prostate Cancer
Mahal, Brandon Prostate Cancer Outcomes and Genomic-Risk differences between African-American and White Men across Gleason Scores
Makarov, Danil The Development and Implementation of the Prostate Cancer Imaging Stewardship (PCIS) Intervention
Markowski, Mark A Single Arm, Open Label Phase II trial of Bipolar Androgen Therapy in Men with Metastatic Castration Resistant Prostate Cancer (mCRPC): A Comparison of Post-Abiraterone vs. PostEnzalutamide Patients. (RESTORE TRIAL)
Mateo, Joaquin Developing a tissue immunofluorescence-based assay to identify homologous recombination deficient prostate cancers towards patient stratification for treatment
Maxwell, Kara Implication of Gleason score for the precision medicine treatment of patients with localized prostate cancer
Mitsiades, Nicholas K-11706 exerts potent anti-cancer activity via suppression of GATA2/AR/cMyc signaling axis in castration resistant prostate cancer
Miyamoto, David Circulating Tumor Cells and Ra-223 Response in Metastatic Castration-Resistant Prostate Cancer
Montie, Heather AR acetylation modulates growth and viability of castrate-resistant prostate tumors
Morrissey, Colm RNA splicing factors SRRM3 and SRRM4 promote cellular plasticity in castration-resistant prostate cancer
Mouw, Kent ATM Loss Confers Greater Sensitivity to ATR Inhibition than PARP Inhibition in Preclinical Prostate Cancer Models
Mu, Ping Loss of CHD1 promotes chromatin dysregulation leading to heterogeneous mechanisms of resistance to hormone therapy in prostate cancer
Mucci, Lorelei Patient Reported Outcomes Among Men with Advanced Prostate Cancer: Results from The IRONMAN Registry
Narayan, Vivek Initial Dose-Escalation and Clinical Results from a Phase 1 Trial of PSMAredirected/TGFβ-insensitive CAR-T cells in Metastatic Castration-Resistant Prostate Cancer
Nickols, Nicholas Phase I Trial of Stereotactic Body Radiotherapy Neoadjuvant to Radical Prostatectomy for Patients with High-Risk Non-Metastatic Prostate Cancer: Feasibility, Safety, and Translational Assessment of the Immune Environment of the Irradiated Prostates
Niknafs, Yashar Retrospective analysis of the performance of MiPS in patients having had multi-parametric MRI
Oksala, Riikka CYP11A1 inhibition as a therapeutic approach for the treatment of castration resistant prostate cancer
Oh, David Single cell discrimination of immunotherapy-induced changes in the prostate tumor microenvironment
Pachynski, Russell A PILOT TRIAL OF NEOANTIGEN DNA VACCINE IN COMBINATION WITH NIVOLUMAB/IPILIMUMAB AND PROSTVAC IN METASTATIC HORMONE-SENSITIVE PROSTATE CANCER
Patnaik, Akash STING Activation to Overcome Resistance to Immune Checkpoint Blockade in PTEN-deficient Prostate Cancer
Perez-Lopez, Raquel Machine learning-based signature integrating radiomics and clinical data predicts response to immune checkpoint inhibitors in solid tumors.
Pilie, Patrick Inhibitors of Ataxia-Telangiectasia Related (ATR) protein lead to innate immune pathway activation and enhanced response to immune therapy
Pippa, Raffaella Mechanistic study of the tumor suppressor role of MITF uncovers actionable translation targeting for prostate cancer.
Pitchiaya, Sethu Unraveling molecular heterogeneities in advanced prostate cancer at single cell resolution
Posadas, Edwin The NanoVelcro CTC-RNA assay: a new method for contemporary genomics and precision medicine via liquid biopsy
Qiao, Yuanyuan Therapeutic targeting autophagy to sensitize cancer immunotherapy in prostate cancer
Quigley, David Whole-Genome and Transcriptional Analysis of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer Demonstrates Intraclass Heterogeneity
Reder, Nicholas Non-destructive 3D pathology with open-top light-sheet microscopy
Reichert, Zachery Non-invasive interrogation of oligometastatic castration-resistant prostate cancer and the benefit of metastasis directed therapy in the phase II FORCE randomized clinical trial
Rescigno, Pasquale Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.
Rodriguez-Bravo, Veronica Dissecting NUP-regulated pathways in aggressive prostate cancer.
Russo, Joshua HER2-Mediated Mechanisms of Resistance to Androgen Deprivation Therapies in Advanced Castration-Resistant Prostate Cancer (CRPC)
Salami, Simpa Development of a Whole-Urine, Next Generation Sequencing-Based Assay for Early Detection of Aggressive Prostate Cancer
Shafi, Ayesha Patient Derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response
Sharp, Adam Clinical Utility of Circulating Tumour Cell Androgen Receptor Splice Variant-7 Status in Metastatic Castration-resistant Prostate Cancer
Shelton, Jeremy Establishing a Prostate Cancer Data Core in VHA: Early Results
Shenderov, Eugene Profiling Anti-tumor Immunity in High-Risk Localized Prostate Cancer after Treatment Targeting the B7-H3 Checkpoint
Spratt, Daniel Two Years of Anti-Androgen Treatment Increases Other-Cause Mortality in Men Receiving Early Salvage Radiotherapy: A Secondary Analysis of the NRG Oncology/RTOG 9601 Randomized Phase III Trial
Stopsack, Konrad Aneuploidy drives lethal progression in prostate cancer
Stoyanova, Tanya Trop2 as a Novel Driver and Therapeutic Target for Metastatic Castration-Resistant Prostate Cancer with Neuroendocrine Phenotype
Strand, Douglas Urethral epithelia extend into the proximal prostate stem cell niche and are increased in prostate cancer
Stuart, Joshua Transcriptional signatures provide alternative views of mCRPC pathological subtypes
Teplensky, Michelle Rational Vaccinology for Prostate Cancer Using Spherical Nucleic Acids
Thaper, Daksh Discovery and characterization of first-in-field BRN2 inhibitors as a treatment strategy for Neuroendocrine Prostate Cancer
Ulmert, David Genetic signature of prostate cancer resistant to optimized hK2 targeted alpha-particle therapy
Vaishampayan, Ulka Phase II Trial of a Novel Immunotherapy Combination of Pembrolizumab and HER2Bi-armed Activated T Cells (BATS) in Metastatic Castrate Resistant Prostate Cancer
Vander Griend, Donald MEIS-Mediated Suppression of Prostate Cancer Growth and Metastasis Through HOXB13- Dependent Regulation of Proteoglycans
VanderWeele, David Organoid culture screen for combination therapies to target aggressive variant prostate cancer
Viswanathan, Srinivas Functional genetic and genomic characterization of androgen receptor signaling in castration-resistant prostate cancer
Viswanathan, Vasanthi Targeting the androgen-indifferent state of prostate cancer through ferroptosis induction
Wilkinson, Scott Integrated radiologic, genomic and pathologic analysis revealed intratumoral divergent responses to neoadjuvant anti-androgen therapy
Wise, David A Parallel Arm Phase 1b/2a Study of DKN-01 as Monotherapy or in Combination with Docetaxel for the Treatment of Advanced Prostate Cancer with Elevated DKK1
Wu, Anjui Genome-wide cfDNA analysis of metastatic prostate cancer
Wyatt, Alexander Detection and characterization of mismatch repair defective metastatic prostate cancer using circulating tumour DNA
Yamaguchi, Yuki Modeling the human prostate tumor microenvironment to develop a novel chimeric antigen receptor T cell therapy
Yang, Rendong Comprehensive Analysis of Exitron Splicing in Human Cancer
Yunger, Sharon Tumor Infiltrating Lymphocytes from human prostate tumors reveal anti-tumor reactivity and potential for adoptive cell therapy
Zhao, Di The Cell–Extrinsic role of CHD1 in Prostate Cancer Development and Progression